{"id":5326,"date":"2021-03-03T11:43:21","date_gmt":"2021-03-03T11:43:21","guid":{"rendered":"https:\/\/www.pavlatou.gr\/?page_id=5326"},"modified":"2024-04-22T11:24:23","modified_gmt":"2024-04-22T11:24:23","slug":"cushings-syndrome","status":"publish","type":"page","link":"https:\/\/www.pavlatou.gr\/en\/cushings-syndrome\/","title":{"rendered":"Cushing&#8217;s  Syndrome"},"content":{"rendered":"\t<section class=\"section\" id=\"section_1152342643\">\n\t\t<div class=\"bg section-bg fill bg-fill  bg-loaded\" >\n\n\t\t\t\n\t\t\t\n\t\t\t\n\n\t\t<\/div>\n\n\t\t\n\n\t\t<div class=\"section-content relative\">\n\t\t\t\n\n  <div class=\"banner has-hover\" id=\"banner-440418326\">\n          <div class=\"banner-inner fill\">\n        <div class=\"banner-bg fill\" >\n            <div class=\"bg fill bg-fill \"><\/div>\n                        <div class=\"overlay\"><\/div>            \n                    <\/div>\n\t\t\n        <div class=\"banner-layers container\">\n            <div class=\"fill banner-link\"><\/div>            \n   <div id=\"text-box-1927451343\" class=\"text-box banner-layer x0 md-x0 lg-x0 y50 md-y50 lg-y50 res-text\">\n                                <div class=\"text-box-content text dark\">\n              \n              <div class=\"text-inner text-left\">\n                  \n\t<div id=\"text-3370322094\" class=\"text\">\n\t\t\n<h3>CUSHING&#8217;S SYNDROME<\/h3>\n<p>Cushing&#8217;s syndrome is caused by elevated cortisol levels with multisystemic consequences<\/p>\n\t\t\n<style>\n#text-3370322094 {\n  color: rgb(255,255,255);\n}\n#text-3370322094 > * {\n  color: rgb(255,255,255);\n}\n<\/style>\n\t<\/div>\n\t\n              <\/div>\n           <\/div>\n                            \n<style>\n#text-box-1927451343 .text-box-content {\n  background-color: rgba(255, 255, 255, 0.16);\n  font-size: 100%;\n}\n#text-box-1927451343 .text-inner {\n  padding: 0px 0px 0px 20px;\n}\n#text-box-1927451343 {\n  width: 60%;\n}\n<\/style>\n    <\/div>\n \n        <\/div>\n      <\/div>\n\n            \n<style>\n#banner-440418326 {\n  padding-top: 600px;\n}\n#banner-440418326 .bg.bg-loaded {\n  background-image: url(https:\/\/www.pavlatou.gr\/wp-content\/uploads\/2024\/04\/Cushings-syndrome-1-1200x800.jpg);\n}\n#banner-440418326 .overlay {\n  background-color: rgba(0, 0, 0, 0.17);\n}\n<\/style>\n  <\/div>\n\n\n\t\t<\/div>\n\n\t\t\n<style>\n#section_1152342643 {\n  padding-top: 30px;\n  padding-bottom: 30px;\n}\n<\/style>\n\t<\/section>\n\t\n\t<section class=\"section\" id=\"section_1416988617\">\n\t\t<div class=\"bg section-bg fill bg-fill  bg-loaded\" >\n\n\t\t\t\n\t\t\t\n\t\t\t\n\n\t\t<\/div>\n\n\t\t\n\n\t\t<div class=\"section-content relative\">\n\t\t\t\n<div class=\"row\"  id=\"row-307202617\">\n\n\t<div id=\"col-1660372144\" class=\"col medium-3 small-12 large-3 col-divided\"  >\n\t\t\t\t<div class=\"col-inner text-left\"  >\n\t\t\t\n\t\t\t\n\t<div class=\"ux-menu stack stack-col justify-start ux-menu--divider-solid\">\n\t\t\n\t<div class=\"ux-menu-link flex menu-item first-menu-item\">\n\t\t<a class=\"ux-menu-link__link flex\" href=\"https:\/\/www.pavlatou.gr\/en\/cushings-syndrome\/#ti-einai\" >\n\t\t\t\t\t\t<span class=\"ux-menu-link__text\">\n\t\t\t\tWhat is Cushing&#039;s Syndrome?\t\t\t<\/span>\n\t\t<\/a>\n\t<\/div>\n\t\n\t<div class=\"ux-menu-link flex menu-item first-menu-item\">\n\t\t<a class=\"ux-menu-link__link flex\" href=\"https:\/\/www.pavlatou.gr\/en\/cushings-syndrome\/#syxnothta\" >\n\t\t\t\t\t\t<span class=\"ux-menu-link__text\">\n\t\t\t\tHow common is it?\t\t\t<\/span>\n\t\t<\/a>\n\t<\/div>\n\t\n\t<div class=\"ux-menu-link flex menu-item first-menu-item\">\n\t\t<a class=\"ux-menu-link__link flex\" href=\"https:\/\/www.pavlatou.gr\/en\/cushings-syndrome\/#aitia\" >\n\t\t\t\t\t\t<span class=\"ux-menu-link__text\">\n\t\t\t\tWhat are the causes of Cushing&#039;s Syndrome?\t\t\t<\/span>\n\t\t<\/a>\n\t<\/div>\n\t\n\t<div class=\"ux-menu-link flex menu-item first-menu-item\">\n\t\t<a class=\"ux-menu-link__link flex\" href=\"https:\/\/www.pavlatou.gr\/en\/cushings-syndrome\/#symptwmata\" >\n\t\t\t\t\t\t<span class=\"ux-menu-link__text\">\n\t\t\t\tWhat are the symptoms and signs of Cushing&#039;s syndrome?\t\t\t<\/span>\n\t\t<\/a>\n\t<\/div>\n\t\n\t<div class=\"ux-menu-link flex menu-item first-menu-item\">\n\t\t<a class=\"ux-menu-link__link flex\" href=\"https:\/\/www.pavlatou.gr\/en\/cushings-syndrome\/#epiplokes\" >\n\t\t\t\t\t\t<span class=\"ux-menu-link__text\">\n\t\t\t\tWhat are the complications of Cushing&#039;s syndrome?\t\t\t<\/span>\n\t\t<\/a>\n\t<\/div>\n\t\n\t<div class=\"ux-menu-link flex menu-item first-menu-item\">\n\t\t<a class=\"ux-menu-link__link flex\" href=\"https:\/\/www.pavlatou.gr\/en\/cushings-syndrome\/#diagnosi\" >\n\t\t\t\t\t\t<span class=\"ux-menu-link__text\">\n\t\t\t\tHow is Cushing&#039;s syndrome diagnosed?\t\t\t<\/span>\n\t\t<\/a>\n\t<\/div>\n\t\n\t<div class=\"ux-menu-link flex menu-item first-menu-item\">\n\t\t<a class=\"ux-menu-link__link flex\" href=\"https:\/\/www.pavlatou.gr\/en\/cushings-syndrome\/#therapeia\" >\n\t\t\t\t\t\t<span class=\"ux-menu-link__text\">\n\t\t\t\tHow is Cushing&#039;s syndrome treated?\t\t\t<\/span>\n\t\t<\/a>\n\t<\/div>\n\t\n\t<div class=\"ux-menu-link flex menu-item first-menu-item\">\n\t\t<a class=\"ux-menu-link__link flex\" href=\"https:\/\/www.pavlatou.gr\/en\/cushings-syndrome\/#einai-epikindyno\" >\n\t\t\t\t\t\t<span class=\"ux-menu-link__text\">\n\t\t\t\tIs Cushing&#039;s Syndrome dangerous?\t\t\t<\/span>\n\t\t<\/a>\n\t<\/div>\n\t\n\t<\/div>\n\t\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-1875196159\" class=\"col medium-8 small-12 large-8\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<h2 id=\"ti-einai\" style=\"font-size: 20px;\">What is Cushing&#8217;s Syndrome?<\/h2>\n<div class=\"is-divider divider clearfix\" style=\"max-width:30%;background-color:rgb(155, 0, 128);\"><\/div>\n\t<div id=\"gap-1568089753\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-1568089753 {\n  padding-top: 20px;\n}\n<\/style>\n\t<\/div>\n\t\n<p>Cushing&#8217;s syndrome is the disease that results from exposing the body to high levels of cortisol for too long. The rise of cortisol in the blood, at high levels for a long time, results either because it is administered exogenously, or because it is abnormally produced in large amounts in the body.<\/p>\n<a href=\"https:\/\/www.pavlatou.gr\/en\/cushing-s-disease\/#ti-einai\" class=\"button secondary is-link is-xsmall lowercase\"  >\n    <span>Top<\/span>\n  <i class=\"icon-angle-right\" aria-hidden=\"true\" ><\/i><\/a>\n\n\t<div id=\"gap-455828187\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-455828187 {\n  padding-top: 50px;\n}\n<\/style>\n\t<\/div>\n\t\n<h2 id=\"syxnothta\" style=\"font-size: 20px;\">How common is it?<\/h2>\n<div class=\"is-divider divider clearfix\" style=\"max-width:30%;background-color:rgb(155, 0, 128);\"><\/div>\n\t<div id=\"gap-610176196\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-610176196 {\n  padding-top: 20px;\n}\n<\/style>\n\t<\/div>\n\t\n<p>Cushing&#8217;s syndrome resulting iatrogenically, from exogenously administered cortisone to treat various diseases is quite common. However, Cushing&#8217;s syndrome resulting from abnormal cortisol production by a tumour is quite rare with an incidence of 2-3 cases per million population per year.<\/p>\n<a href=\"https:\/\/www.pavlatou.gr\/en\/cushing-s-disease\/#ti-einai\" class=\"button secondary is-link is-xsmall lowercase\"  >\n    <span>Top<\/span>\n  <i class=\"icon-angle-right\" aria-hidden=\"true\" ><\/i><\/a>\n\n\t<div id=\"gap-1061702717\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-1061702717 {\n  padding-top: 50px;\n}\n<\/style>\n\t<\/div>\n\t\n<h2 id=\"aitia\" style=\"font-size: 20px;\">What are the causes of Cushing&#8217;s Syndrome?<\/h2>\n<div class=\"is-divider divider clearfix\" style=\"max-width:30%;background-color:rgb(155, 0, 128);\"><\/div>\n\t<div id=\"gap-1429139102\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-1429139102 {\n  padding-top: 20px;\n}\n<\/style>\n\t<\/div>\n\t\n<p>The causes of Cushing&#8217;s Syndrome are:<\/p>\n<ul>\n<li>Administration of cortisone exogenously, such as for the treatment of autoimmune diseases<\/li>\n<li>A <a href=\"https:\/\/www.pavlatou.gr\/en\/adenomata-ypofysis\/\">Pituitary neuroendocrine tumour<\/a> that creates excess ACTH (pituitary adenoma).<\/li>\n<li>A Neuroendocrine tumour of lung, thymus, pancreas, thyroid gland that hypersecretes ACTH. These tumours can be benign or malignant.<\/li>\n<li>An <a href=\"https:\/\/www.pavlatou.gr\/en\/ogkoi-epinefridiwn\/\">Adrenal tumour (adenoma)<\/a> that hypersecretes cortisol<\/li>\n<\/ul>\n<a href=\"https:\/\/www.pavlatou.gr\/en\/cushing-s-disease\/#ti-einai\" class=\"button secondary is-link is-xsmall lowercase\"  >\n    <span>Top<\/span>\n  <i class=\"icon-angle-right\" aria-hidden=\"true\" ><\/i><\/a>\n\n\t<div id=\"gap-751897361\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-751897361 {\n  padding-top: 50px;\n}\n<\/style>\n\t<\/div>\n\t\n<h2 id=\"symptwmata\" style=\"font-size: 20px;\">What are the symptoms and signs of Cushing&#8217;s syndrome?<\/h2>\n<div class=\"is-divider divider clearfix\" style=\"max-width:30%;background-color:rgb(155, 0, 128);\"><\/div>\n\t<div id=\"gap-2111411338\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-2111411338 {\n  padding-top: 20px;\n}\n<\/style>\n\t<\/div>\n\t\n<ul>\n<li>Weight gain<\/li>\n<li>Round (Moon) face<\/li>\n<li>Buffalo Hump (increased fat at the base of the neck)<\/li>\n<li>Purple stretch marks<\/li>\n<li>Easy bruising<\/li>\n<li>Acne<\/li>\n<li>Hypertrichosis<\/li>\n<li>Difficulty in healing wounds<\/li>\n<li>Muscle weakness<\/li>\n<li>Depression<\/li>\n<li><a href=\"https:\/\/www.pavlatou.gr\/en\/ypogonimothta\/\">Infertility<\/a><\/li>\n<li><a href=\"https:\/\/www.pavlatou.gr\/en\/diataraxes-tou-kuklou\/\">Menstrual Irregularities<\/a><\/li>\n<li><a href=\"https:\/\/www.pavlatou.gr\/en\/stytikh-dysleitourgia\/\">Erectile dysfunction<\/a><\/li>\n<\/ul>\n<a href=\"https:\/\/www.pavlatou.gr\/en\/cushing-s-disease\/#ti-einai\" class=\"button secondary is-link is-xsmall lowercase\"  >\n    <span>Top<\/span>\n  <i class=\"icon-angle-right\" aria-hidden=\"true\" ><\/i><\/a>\n\n\t<div id=\"gap-1911405884\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-1911405884 {\n  padding-top: 50px;\n}\n<\/style>\n\t<\/div>\n\t\n<p><img fetchpriority=\"high\" decoding=\"async\" class=\"alignnone size-medium wp-image-3080\" src=\"https:\/\/www.pavlatou.gr\/wp-content\/uploads\/2021\/03\/kidneys-711x400.jpg\" alt=\"\u039d\u03b5\u03c6\u03c1\u03ac \u03b5\u03c0\u03b9\u03bd\u03b5\u03c6\u03c1\u03af\u03b4\u03b9\u03b1 - \u03a3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf Cushing\" width=\"711\" height=\"400\" srcset=\"https:\/\/www.pavlatou.gr\/wp-content\/uploads\/2021\/03\/kidneys-711x400.jpg 711w, https:\/\/www.pavlatou.gr\/wp-content\/uploads\/2021\/03\/kidneys-768x432.jpg 768w, https:\/\/www.pavlatou.gr\/wp-content\/uploads\/2021\/03\/kidneys.jpg 1070w\" sizes=\"(max-width: 711px) 100vw, 711px\" \/><\/p>\n\t<div id=\"gap-955056767\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-955056767 {\n  padding-top: 50px;\n}\n<\/style>\n\t<\/div>\n\t\n<h2 id=\"epiplokes\" style=\"font-size: 20px;\">What are the complications of Cushing&#8217;s syndrome?<\/h2>\n<div class=\"is-divider divider clearfix\" style=\"max-width:30%;background-color:rgb(155, 0, 128);\"><\/div>\n\t<div id=\"gap-1186788495\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-1186788495 {\n  padding-top: 20px;\n}\n<\/style>\n\t<\/div>\n\t\n<p>The complications of Cushing&#8217;s syndrome depend on the severity of the disease and its duration:<\/p>\n<ul>\n<li>Osteopenia, Osteoporosis, Fractures<\/li>\n<li><a href=\"https:\/\/www.pavlatou.gr\/en\/endokrinikh-ypertash\/\">Hypertension<\/a><\/li>\n<li>Arrhythmias<\/li>\n<li>Cardiomyopathy<\/li>\n<li>High Cardiovascular Risk<\/li>\n<li><a href=\"https:\/\/www.pavlatou.gr\/en\/sakcharodis-diavitis\/\">Diabetes<\/a><\/li>\n<li>Hyperlipidemia<\/li>\n<li>Immunosuppression, frequent and rare infections<\/li>\n<li>Psychosis<\/li>\n<li>Thromboembolic events<\/li>\n<li>Death<\/li>\n<\/ul>\n<a href=\"https:\/\/www.pavlatou.gr\/en\/cushing-s-disease\/#ti-einai\" class=\"button secondary is-link is-xsmall lowercase\"  >\n    <span>Top<\/span>\n  <i class=\"icon-angle-right\" aria-hidden=\"true\" ><\/i><\/a>\n\n\t<div id=\"gap-2067564987\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-2067564987 {\n  padding-top: 50px;\n}\n<\/style>\n\t<\/div>\n\t\n<h2 id=\"diagnosi\" style=\"font-size: 20px;\">How is Cushing&#8217;s syndrome diagnosed?<\/h2>\n<div class=\"is-divider divider clearfix\" style=\"max-width:30%;background-color:rgb(155, 0, 128);\"><\/div>\n\t<div id=\"gap-826885677\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-826885677 {\n  padding-top: 20px;\n}\n<\/style>\n\t<\/div>\n\t\n<p>The diagnosis of Cushing&#8217;s syndrome requires complex endocrine tests, extensive experience in interpreting the results and a specialized center. It includes history, physical examination and blood tests. Sometimes it can take a long time to make a diagnosis. Finding the cause is also difficult and involves, among other things, neuroimaging, and even then, the cause may not be found. A specialized multidisciplinary team is required to diagnose the syndrome, identify its cause and plan the best treatment.<\/p>\n<a href=\"https:\/\/www.pavlatou.gr\/en\/cushing-s-disease\/#ti-einai\" class=\"button secondary is-link is-xsmall lowercase\"  >\n    <span>Top<\/span>\n  <i class=\"icon-angle-right\" aria-hidden=\"true\" ><\/i><\/a>\n\n\t<div id=\"gap-1666106588\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-1666106588 {\n  padding-top: 50px;\n}\n<\/style>\n\t<\/div>\n\t\n<h2 id=\"therapeia\" style=\"font-size: 20px;\">How is Cushing&#8217;s syndrome treated?<\/h2>\n<div class=\"is-divider divider clearfix\" style=\"max-width:30%;background-color:rgb(155, 0, 128);\"><\/div>\n\t<div id=\"gap-1348221572\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-1348221572 {\n  padding-top: 20px;\n}\n<\/style>\n\t<\/div>\n\t\n<p>Treatment of the syndrome depends on its cause. If it is caused by external cortisone administration, a gradual reduction in dose is required. If the syndrome is due to a tumor, the treatment is surgical removal. However, many times a combination of treatments is needed which may include:<\/p>\n<ul>\n<li>surgical removal<\/li>\n<li>radiation and<\/li>\n<li>drugs that lower cortisol levels.<\/li>\n<\/ul>\n<a href=\"https:\/\/www.pavlatou.gr\/en\/cushing-s-disease\/#ti-einai\" class=\"button secondary is-link is-xsmall lowercase\"  >\n    <span>Top<\/span>\n  <i class=\"icon-angle-right\" aria-hidden=\"true\" ><\/i><\/a>\n\n\t<div id=\"gap-286818607\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-286818607 {\n  padding-top: 50px;\n}\n<\/style>\n\t<\/div>\n\t\n<h2 id=\"einai-epikindyno\" style=\"font-size: 20px;\">Is Cushing&#8217;s Syndrome dangerous?<\/h2>\n<div class=\"is-divider divider clearfix\" style=\"max-width:30%;background-color:rgb(155, 0, 128);\"><\/div>\n\t<div id=\"gap-83166024\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-83166024 {\n  padding-top: 20px;\n}\n<\/style>\n\t<\/div>\n\t\n<p>When Cushing&#8217;s syndrome is due to a tumor, it is usually a <em>rare, slow-growing, benign but potentially fatal<\/em> tumor. The 5-year survival of untreated severe hypercortisolism (elevated blood cortisol levels) is 50%. On the other hand, if it is due to a malignant tumor the prognosis is even worse.<\/p>\n<a href=\"https:\/\/www.pavlatou.gr\/en\/cushing-s-disease\/#ti-einai\" class=\"button secondary is-link is-xsmall lowercase\"  >\n    <span>Top<\/span>\n  <i class=\"icon-angle-right\" aria-hidden=\"true\" ><\/i><\/a>\n\n\t<div id=\"gap-1738512819\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-1738512819 {\n  padding-top: 50px;\n}\n<\/style>\n\t<\/div>\n\t\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n<\/div>\n\t\t<\/div>\n\n\t\t\n<style>\n#section_1416988617 {\n  padding-top: 30px;\n  padding-bottom: 30px;\n}\n<\/style>\n\t<\/section>\n\t\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":5,"featured_media":0,"parent":0,"menu_order":432,"comment_status":"closed","ping_status":"closed","template":"page-blank.php","meta":{"footnotes":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Cushing&#039;s syndrome and treatment by Dr. Maria Pavlatou |<\/title>\n<meta name=\"description\" content=\"Diagnosis and treatment of Cushing&#039;s syndrome by the experienced endocrinologist-diabetologist Dr. Maria Pavlatou.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pavlatou.gr\/en\/cushings-syndrome\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Cushing&#039;s syndrome and treatment by Dr. Maria Pavlatou |\" \/>\n<meta property=\"og:description\" content=\"Diagnosis and treatment of Cushing&#039;s syndrome by the experienced endocrinologist-diabetologist Dr. Maria Pavlatou.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pavlatou.gr\/en\/cushings-syndrome\/\" \/>\n<meta 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