{"id":5279,"date":"2021-04-02T09:31:12","date_gmt":"2021-04-02T09:31:12","guid":{"rendered":"https:\/\/www.pavlatou.gr\/?page_id=5279"},"modified":"2024-04-15T13:52:01","modified_gmt":"2024-04-15T13:52:01","slug":"medullary-thyroid-cancer","status":"publish","type":"page","link":"https:\/\/www.pavlatou.gr\/en\/medullary-thyroid-cancer\/","title":{"rendered":"Medullary Thyroid Cancer"},"content":{"rendered":"\t<section class=\"section\" id=\"section_550930981\">\n\t\t<div class=\"bg section-bg fill bg-fill  bg-loaded\" >\n\n\t\t\t\n\t\t\t\n\t\t\t\n\n\t\t<\/div>\n\n\t\t\n\n\t\t<div class=\"section-content relative\">\n\t\t\t\n\n  <div class=\"banner has-hover\" id=\"banner-1428943402\">\n          <div class=\"banner-inner fill\">\n        <div class=\"banner-bg fill\" >\n            <div class=\"bg fill bg-fill \"><\/div>\n                        <div class=\"overlay\"><\/div>            \n                    <\/div>\n\t\t\n        <div class=\"banner-layers container\">\n            <div class=\"fill banner-link\"><\/div>            \n   <div id=\"text-box-1245229650\" class=\"text-box banner-layer x0 md-x0 lg-x0 y50 md-y50 lg-y50 res-text\">\n                                <div class=\"text-box-content text dark\">\n              \n              <div class=\"text-inner text-left\">\n                  \n<h3>MEDULLARY THYROID CANCER<\/h3>\n<p>Medullary thyroid cancer is a neuroendocrine tumour of the parafollicular cells of the thyroid gland<\/p>\n              <\/div>\n           <\/div>\n                            \n<style>\n#text-box-1245229650 .text-box-content {\n  background-color: rgba(255, 255, 255, 0.16);\n  font-size: 100%;\n}\n#text-box-1245229650 .text-inner {\n  padding: 0px 0px 0px 20px;\n}\n#text-box-1245229650 {\n  width: 60%;\n}\n<\/style>\n    <\/div>\n \n        <\/div>\n      <\/div>\n\n            \n<style>\n#banner-1428943402 {\n  padding-top: 600px;\n}\n#banner-1428943402 .bg.bg-loaded {\n  background-image: url(https:\/\/www.pavlatou.gr\/wp-content\/uploads\/2024\/04\/pexels-anna-tarazevich-8016903-1200x800.jpg);\n}\n#banner-1428943402 .overlay {\n  background-color: rgba(0, 0, 0, 0.17);\n}\n<\/style>\n  <\/div>\n\n\n\t\t<\/div>\n\n\t\t\n<style>\n#section_550930981 {\n  padding-top: 30px;\n  padding-bottom: 30px;\n}\n<\/style>\n\t<\/section>\n\t\n\t<section class=\"section\" id=\"section_773358706\">\n\t\t<div class=\"bg section-bg fill bg-fill  bg-loaded\" >\n\n\t\t\t\n\t\t\t\n\t\t\t\n\n\t\t<\/div>\n\n\t\t\n\n\t\t<div class=\"section-content relative\">\n\t\t\t\n<div class=\"row\"  id=\"row-1401213469\">\n\n\t<div id=\"col-1368748695\" class=\"col medium-3 small-12 large-3 col-divided\"  >\n\t\t\t\t<div class=\"col-inner text-left\"  >\n\t\t\t\n\t\t\t\n\t<div class=\"ux-menu stack stack-col justify-start ux-menu--divider-solid\">\n\t\t\n\t<div class=\"ux-menu-link flex menu-item first-menu-item\">\n\t\t<a class=\"ux-menu-link__link flex\" href=\"https:\/\/www.pavlatou.gr\/en\/medullary-thyroid-cancer\/#ti-einai\" >\n\t\t\t\t\t\t<span class=\"ux-menu-link__text\">\n\t\t\t\tWhat is medullary thyroid cancer ?\t\t\t<\/span>\n\t\t<\/a>\n\t<\/div>\n\t\n\t<div class=\"ux-menu-link flex menu-item first-menu-item\">\n\t\t<a class=\"ux-menu-link__link flex\" href=\"https:\/\/www.pavlatou.gr\/en\/medullary-thyroid-cancer\/#syxnothta\" >\n\t\t\t\t\t\t<span class=\"ux-menu-link__text\">\n\t\t\t\tHow common is it and at what age does it occur?\t\t\t<\/span>\n\t\t<\/a>\n\t<\/div>\n\t\n\t<div class=\"ux-menu-link flex menu-item first-menu-item\">\n\t\t<a class=\"ux-menu-link__link flex\" href=\"https:\/\/www.pavlatou.gr\/en\/medullary-thyroid-cancer\/#klironomikotita\" >\n\t\t\t\t\t\t<span class=\"ux-menu-link__text\">\n\t\t\t\tIs this cancer inherited and how it presents?\t\t\t<\/span>\n\t\t<\/a>\n\t<\/div>\n\t\n\t<div class=\"ux-menu-link flex menu-item first-menu-item\">\n\t\t<a class=\"ux-menu-link__link flex\" href=\"https:\/\/www.pavlatou.gr\/en\/medullary-thyroid-cancer\/#symptwmata\" >\n\t\t\t\t\t\t<span class=\"ux-menu-link__text\">\n\t\t\t\tWhat are the signs and symptoms of medullary thyroid cancer?\t\t\t<\/span>\n\t\t<\/a>\n\t<\/div>\n\t\n\t<div class=\"ux-menu-link flex menu-item first-menu-item\">\n\t\t<a class=\"ux-menu-link__link flex\" href=\"https:\/\/www.pavlatou.gr\/en\/medullary-thyroid-cancer\/#diagnosi\" >\n\t\t\t\t\t\t<span class=\"ux-menu-link__text\">\n\t\t\t\tHow is medullary thyroid cancer diagnosed?\t\t\t<\/span>\n\t\t<\/a>\n\t<\/div>\n\t\n\t<div class=\"ux-menu-link flex menu-item first-menu-item\">\n\t\t<a class=\"ux-menu-link__link flex\" href=\"https:\/\/www.pavlatou.gr\/en\/medullary-thyroid-cancer\/#therapeia\" >\n\t\t\t\t\t\t<span class=\"ux-menu-link__text\">\n\t\t\t\tHow is medullary thyroid cancer treated?\t\t\t<\/span>\n\t\t<\/a>\n\t<\/div>\n\t\n\t<div class=\"ux-menu-link flex menu-item first-menu-item\">\n\t\t<a class=\"ux-menu-link__link flex\" href=\"https:\/\/www.pavlatou.gr\/en\/medullary-thyroid-cancer\/#foreis\" >\n\t\t\t\t\t\t<span class=\"ux-menu-link__text\">\n\t\t\t\tWhat should the mutation carriers do?\t\t\t<\/span>\n\t\t<\/a>\n\t<\/div>\n\t\n\t<\/div>\n\t\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-213837415\" class=\"col medium-8 small-12 large-8\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<h2 id=\"ti-einai\" style=\"font-size: 20px;\">What is medullary thyroid cancer ?<\/h2>\n<div class=\"is-divider divider clearfix\" style=\"max-width:30%;background-color:rgb(155, 0, 128);\"><\/div>\n\t<div id=\"gap-632075146\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-632075146 {\n  padding-top: 20px;\n}\n<\/style>\n\t<\/div>\n\t\n<p>Medullar thyroid cancer is a neuroendocrine tumour arising from\u00a0\u00a0 the parafollicular or C-\u00a0 cells of the <a href=\"https:\/\/www.pavlatou.gr\/en\/thyreoeidhs-adenas\/\">thyroid gland.<\/a><\/p>\n<a href=\"https:\/\/www.pavlatou.gr\/en\/medullary-thyroid-cancer\/#ti-einai\" class=\"button secondary is-link is-xsmall lowercase\"  >\n    <span>Top<\/span>\n  <i class=\"icon-angle-right\" aria-hidden=\"true\" ><\/i><\/a>\n\n\t<div id=\"gap-992916478\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-992916478 {\n  padding-top: 50px;\n}\n<\/style>\n\t<\/div>\n\t\n<h2 id=\"syxnothta\" style=\"font-size: 20px;\">How common is it and at what age does it occur?<\/h2>\n<div class=\"is-divider divider clearfix\" style=\"max-width:30%;background-color:rgb(155, 0, 128);\"><\/div>\n\t<div id=\"gap-2042564773\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-2042564773 {\n  padding-top: 20px;\n}\n<\/style>\n\t<\/div>\n\t\n<p>It is a rare tumour, accounting for 5% of all<a href=\"\/en\/karkinos-toy-thyreoeidoys\/\"> thyroid cancers<\/a>. In the majority of cases, the tumour is sporadic, with a peak incidence at 40-60 years of age.<\/p>\n<a href=\"https:\/\/www.pavlatou.gr\/en\/medullary-thyroid-cancer\/#ti-einai\" class=\"button secondary is-link is-xsmall lowercase\"  >\n    <span>Top<\/span>\n  <i class=\"icon-angle-right\" aria-hidden=\"true\" ><\/i><\/a>\n\n\t<div id=\"gap-54205090\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-54205090 {\n  padding-top: 50px;\n}\n<\/style>\n\t<\/div>\n\t\n<h2 id=\"klironomikotita\" style=\"font-size: 20px;\">Is this cancer inherited and how it presents?<\/h2>\n<div class=\"is-divider divider clearfix\" style=\"max-width:30%;background-color:rgb(155, 0, 128);\"><\/div>\n\t<div id=\"gap-925290735\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-925290735 {\n  padding-top: 20px;\n}\n<\/style>\n\t<\/div>\n\t\n<p>However, in 25% of cases, it is inherited as an autosomal dominant manner, meaning that about 50% of the offspring will inherit the disease from the parent carrying the mutation. The inherited medullary thyroid cancer presents as either familial medullary thyroid cancer without other accompanying endocrine tumors, or in the form of multiple endocrine neoplasia genetic syndromes that appear much earlier in life, <strong>even in childhood<\/strong>:<\/p>\n<ul>\n<li>MEN2A and<\/li>\n<li>MEN2B<\/li>\n<\/ul>\n<a href=\"https:\/\/www.pavlatou.gr\/en\/medullary-thyroid-cancer\/#ti-einai\" class=\"button secondary is-link is-xsmall lowercase\"  >\n    <span>Top<\/span>\n  <i class=\"icon-angle-right\" aria-hidden=\"true\" ><\/i><\/a>\n\n\t<div id=\"gap-917226232\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-917226232 {\n  padding-top: 50px;\n}\n<\/style>\n\t<\/div>\n\t\n<h2 id=\"symptwmata\" style=\"font-size: 20px;\">What are the signs and symptoms of medullary thyroid cancer?<\/h2>\n<div class=\"is-divider divider clearfix\" style=\"max-width:30%;background-color:rgb(155, 0, 128);\"><\/div>\n\t<div id=\"gap-1976904243\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-1976904243 {\n  padding-top: 20px;\n}\n<\/style>\n\t<\/div>\n\t\n<ul>\n<li>A thyroid nodule<\/li>\n<li>Swollen cervical lymph nodes<\/li>\n<li>Difficulty in swallowing<\/li>\n<li>Hoarseness<\/li>\n<li>Diarrhoea<\/li>\n<li>Flashes<\/li>\n<\/ul>\n<a href=\"https:\/\/www.pavlatou.gr\/en\/medullary-thyroid-cancer\/#ti-einai\" class=\"button secondary is-link is-xsmall lowercase\"  >\n    <span>Top<\/span>\n  <i class=\"icon-angle-right\" aria-hidden=\"true\" ><\/i><\/a>\n\n\t<div id=\"gap-196995231\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-196995231 {\n  padding-top: 50px;\n}\n<\/style>\n\t<\/div>\n\t\n<h2 id=\"diagnosi\" style=\"font-size: 20px;\">How is medullary thyroid cancer diagnosed?<\/h2>\n<div class=\"is-divider divider clearfix\" style=\"max-width:30%;background-color:rgb(155, 0, 128);\"><\/div>\n\t<div id=\"gap-2045305956\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-2045305956 {\n  padding-top: 20px;\n}\n<\/style>\n\t<\/div>\n\t\n<p>The diagnosis of medullary thyroid cancer is made by fine needle aspiration (FNA) and calcitonin measurement, followed by genetic analysis (DNA) to exclude hereditary disease. The extent of the disease and any possible metastases is investigated by different imaging modalities.<\/p>\n<a href=\"https:\/\/www.pavlatou.gr\/en\/medullary-thyroid-cancer\/#ti-einai\" class=\"button secondary is-link is-xsmall lowercase\"  >\n    <span>Top<\/span>\n  <i class=\"icon-angle-right\" aria-hidden=\"true\" ><\/i><\/a>\n\n\t<div id=\"gap-512615034\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-512615034 {\n  padding-top: 20px;\n}\n<\/style>\n\t<\/div>\n\t\n\t<div id=\"gap-1279161009\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-1279161009 {\n  padding-top: 50px;\n}\n<\/style>\n\t<\/div>\n\t\n<h2 id=\"therapeia\" style=\"font-size: 20px;\">How is medullary thyroid cancer treated?<\/h2>\n<div class=\"is-divider divider clearfix\" style=\"max-width:30%;background-color:rgb(155, 0, 128);\"><\/div>\n\t<div id=\"gap-951607973\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-951607973 {\n  padding-top: 20px;\n}\n<\/style>\n\t<\/div>\n\t\n<p>The treatment of choice includes total thyroidectomy with lymph node dissection, the extent of which depends on the presence of metastases. In case of relapse, residual disease or metastases, a combination of surgeries, radiation, and newer targeted systemic therapies are implemented. <strong>Regular monitoring<\/strong> and follow-up allow the early diagnosis of possible relapses, while in the inherited form, allows the early diagnosis and treatment of the multiple tumors.<\/p>\n<a href=\"https:\/\/www.pavlatou.gr\/en\/medullary-thyroid-cancer\/#ti-einai\" class=\"button secondary is-link is-xsmall lowercase\"  >\n    <span>Top<\/span>\n  <i class=\"icon-angle-right\" aria-hidden=\"true\" ><\/i><\/a>\n\n\t<div id=\"gap-136452994\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-136452994 {\n  padding-top: 50px;\n}\n<\/style>\n\t<\/div>\n\t\n<h2 id=\"foreis\" style=\"font-size: 20px;\">What should the mutation carriers do?<\/h2>\n<div class=\"is-divider divider clearfix\" style=\"max-width:30%;background-color:rgb(155, 0, 128);\"><\/div>\n\t<div id=\"gap-1032694831\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-1032694831 {\n  padding-top: 20px;\n}\n<\/style>\n\t<\/div>\n\t\n<p>In all carriers of the mutations causing the disease, prophylactic total thyroidectomy in childhood is recommended as the tumor can occur even in the first year of life.<\/p>\n<a href=\"https:\/\/www.pavlatou.gr\/en\/medullary-thyroid-cancer\/#ti-einai\" class=\"button secondary is-link is-xsmall lowercase\"  >\n    <span>Top<\/span>\n  <i class=\"icon-angle-right\" aria-hidden=\"true\" ><\/i><\/a>\n\n\t<div id=\"gap-2146333653\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-2146333653 {\n  padding-top: 50px;\n}\n<\/style>\n\t<\/div>\n\t\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n<\/div>\n\t\t<\/div>\n\n\t\t\n<style>\n#section_773358706 {\n  padding-top: 30px;\n  padding-bottom: 30px;\n}\n<\/style>\n\t<\/section>\n\t\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":5,"featured_media":0,"parent":0,"menu_order":544,"comment_status":"closed","ping_status":"closed","template":"page-blank.php","meta":{"footnotes":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Treatment of Medullary thyroid Carcinoma by Dr. Maria Pavlatou |<\/title>\n<meta name=\"description\" content=\"Diagnosis and treatment of Medullary thyroid carcinoma by the experienced endocrinologist-diabetologist Dr. Maria Pavlatou.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pavlatou.gr\/en\/medullary-thyroid-cancer\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" 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