What is prolactinoma?

Prolactinoma is a benign tumour of the pituitary gland that hyper-secretes prolactin.

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How common is it?

The incidence of prolactinoma is 2.2 per 100,000 people, and it is the most common secreting (functioning) adenoma.

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What are the symptoms and signs?

  • Oligomenorrhea
  • Anovulation
  • Infertility
  • Galactorrhea (milk discharge from the breast)
  • Osteoporosis, osteopenia
  • Vaginal dryness
  • Erectile dysfunction
  • Ηeadaches
  • Vision disturbances (diplopia, bitemporal hemianopsia)
  • Hormonal deficiencies (hypopituitarism)
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How is prolactinoma diagnosed?

The diagnosis of prolactinoma requires a physical examination, history, neuroimaging (e.g. MRI) and hormonal testing, while specialized endocrine tests and ophthalmological testing are often required.

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What is the treatment of prolactinoma?

Prolactinoma is highly responsive to medication. However, sometimes surgical excision, radiation or a combination of these options may be needed while regular monitoring is followed.

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