What is prolactinoma?

Prolactinoma is a benign tumour of the pituitary gland that hyper-secretes prolactin.


How common is it?

The incidence of prolactinoma is 2.2 per 100,000 people, and it is the most common secreting (functioning) adenoma.


What are the symptoms and signs?

  • Oligomenorrhea
  • Anovulation
  • Infertility
  • Galactorrhea (milk discharge from the breast)
  • Osteoporosis, osteopenia
  • Vaginal dryness
  • Erectile dysfunction
  • Ηeadaches
  • Vision disturbances (diplopia, bitemporal hemianopsia)
  • Hormonal deficiencies (hypopituitarism)

How is prolactinoma diagnosed?

The diagnosis of prolactinoma requires a physical examination, history, neuroimaging (e.g. MRI) and hormonal testing, while specialized endocrine tests and ophthalmological testing are often required.


What is the treatment of prolactinoma?

Prolactinoma is highly responsive to medication. However, sometimes surgical excision, radiation or a combination of these options may be needed while regular monitoring is followed.